Clinical Research And Innovation | SightMD Skip to main content

Research

Clinical Research at SightMD

One of the most exciting aspects of medicine is continuous innovation, scientific exploration, and research into how we can provide enhanced care for our patients. The field of ophthalmology has been on the forefront and recipient of revolutionizing technology, novel medications, premium devices, and innovative surgical techniques. Individually or combined, these advancements have provided patients with better vision and improved treatment options.

At SightMD we are continuously coupling efforts with top-tiered patient-centric industry-leading companies to bring the newest techniques, technologies, and medications to our patients through our Department of Clinical Research. Lead by Dr. Alanna Nattis, she has designed, developed, and exclusively accessed investigational treatment studies for wide-ranging ophthalmic conditions such as severe dry eye, glaucoma, refractive and cataract surgery, and retinal pathologies. Having direct access to FDA clinical trials uniquely provides SightMD with state-of-the-art care for our current and future patients.

Ongoing/Currently Enrolling Research Studies

We are currently recruiting for several active clinical trials. Please contact us for more information!

Evaluation of medication-releasing intraocular implant to treat open angle glaucoma and ocular hypertension.

Prospective, Randomized Phase 3 Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, USP 0.5%

  • Principal Investigator (PI): Alanna Nattis, DO
  • Sub-Investigators (Sub-I’s): Richard Nattis MD, Raju Sarwal MD
  • Research Coordinator: Kathy Lemier, Sub-coordinator Mary Iaconis
  • Current patient enrollment: 18
  • Stage of Recruitment: Closed, data being processed
  • Trial type: Phase 3 FDA

In-depth evaluation using high-resolution corneal imaging during and after treatment for patients with neurotrophic keratitis treated with Recombinant Human Nerve Growth Factor (Oxervate)

Using OCT to measure regeneration of the cornea during/after treatment of neurotrophic keratitis with Oxervate

  • PI: Brad Kligman MD
  • Research Coordinator: Monique Murray
  • Current patient enrollment: 3
  • Stage of Recruitment: Open
  • Trial type: IIT

Evaluation of visual outcomes following implantation of specialized intraocular lens in patients without natural crystalline lens (aphakia)

Clinical Investigation of the ARTISAN Aphakia Lens in Adults

  • PI: Alexander Hatsis MD
  • Sub-I: Alanna Nattis DO
  • Research Coordinator: Joann Hatsis RN
  • Current patient enrollment: 10
  • Stage of Recruitment: Open
  • Trial type: Phase 3 FDA
  • Synopsis: Evaluation of visual outcomes following implantation of specialized intraocular lens in patients without natural crystalline lens (aphakia)

Evaluation of dry eye signs and symptoms following cataract surgery in patients receiving a dexamethasone intracanalicular insert vs. topical steroid

Evaluation of Vision Recovery and Comfort Index in Patients with Borderline/Mild Dry Eyes Undergoing Femtosecond Laser Assisted Cataract Surgery with Premium Intraocular Lens

  • PI: John Passarelli MD
  • Research Coordinator: Marshell Singleton RN
  • Current patient enrollment: 30
  • Stage of Recruitment: Closed, data being processed
  • Trial type: IIT

Evaluation of new extended vision (“extended depth of focus”) intraocular lens implant on visual success and quality of life following implantation during routine cataract surgery

Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement (Vivity)

  • PI: Alanna Nattis DO
  • Sub-I: Eric Rosenberg DO, Richard Nattis MD, John Passarelli MD, Jordan Garelick MD, Craig Richter MD
  • Research Coordinator: Kathy Lemier
  • Current patient enrollment: 46
  • Stage of Recruitment: Closed, data being processed
  • Trial type: IIT

Evaluation of speed of visual recovery in cataract surgery patients undergoing surgery using a traditional operative microscope vs. a lower-light intensity, 3-D system

Prospective randomized evaluation and comparison of the effect of decreased illumination on visual recovery following cataract surgery

  • PI: Eric Rosenberg DO
  • Sub-I: Alanna Nattis DO
  • Research Coordinator: Mary Iaconis
  • Current patient enrollment: 215
  • Stage of Recruitment: Closed, data being processed
  • Trial type: IIT

Eye exams provided to patients undergoing investigational research for novel chemotherapeutics/therapeutic regimens across the greater NYC area and Long Island

PI: several physicians across SightMD locations
Stage of Recruitment: Open

A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512, a Cold Thermoreceptor Modulator, for the Treatment of Dry Eye Disease (COMET-4)

Evaluation of a novel eye drop to help treat dry eye,particularly those who have not responded successfully to currently available dry eye therapies

  • PI: Brad Kligman, MD
  • Research Coordinator: Monique Murray
  • Stage of Recruitment: Open
  • Trial Type: Phase 3 FDA

Designed to gather data to further understand genetic risk factors associated with AMD

  • PI: Edward Marcus, MD
  • Research Coordinator: Megan Cunnius
  • Stage of Recruitment: Open
  • Trial Type: Pilot/Epidemiological

A multi-center, randomized, double-masked, vehicle-controlled, parallel-group, study to
evaluate the safety and efficacy of CSB-001 Ophthalmic Solution 0.1% in Stage 2 and 3
Neurotrophic Keratitis Subjects

Evaluation of a novel eyedrop to help treat stage 2 and 3 neurotrophic keratitis (non-healing epithelial defects and ulcers)

  • PI: Alanna Nattis, DO
  • Sub-I: Eric Rosenberg, DO
  • Research Coordinator: Kathy Lemier
  • Stage of Recruitment: Open
  • Trial Type: Phase 2

Evaluation of patient and provider perceptions and knowledge regarding diagnosis and treatment of demodex blepharitis in a real-world setting

  • PI: Alanna Nattis, DO
  • Sub-I: Eric Rosenberg, DO
  • Research Coordinator: Kathy Lemier
  • Stage of Recruitment: Open
  • Trial type: Observational post-market

A Real World Evidence (RWE) Long-Term Follow-Up Study to Assess Outcomes of Alcon Monofocal Intraocular Lenses

Evaluation in a long-term follow up time frame of the AcrySof single-piece and AcrySof multi-piece monofocal intraocular lenses

  • PI: Alanna Nattis, DO
  • Sub-I: Eric Rosenberg, DO
  • Research Coordinator: Kathy Lemier
  • Stage of Recruitment: Open
  • Trial Type: Phase 4 post-market

Long-term evaluation of safety and performance of Clareon Presbyopia Correcting IOLs – PMCF Study of Clareon Vivity & Clareon PanOptix

Long-term evaluation of patients post-bilateral implantation of Clareon Panoptix and/or Vivity intraocular lenses

  • PI: Alanna Nattis, DO
  • Sub-I: Eric Rosenberg, DO
  • Research Coordinator: Kathy Lemier
  • Stage of Recruitment: Open
  • Trial type: Phase 4, post-market

Soon-to-be-Enrolling Studies

We will be looking open up the following clinical trials soon. Please contact us for more information!

Evaluation of patient characteristics with signs and symptoms of dry eye and positive correlation with presence of Demodex mites

Correlation of Collarettes and Demodex with ocular surface signs and symptoms

  • PI: Alanna Nattis DO
  • Sub-I: Eric Rosenberg DO
  • Research Coordinator: Kathy Lemier
  • Trial type: IIT

Sign up for our newsletter

Stay up to date on the latest news, promotions, and research topics from across SightMD.

Subscribe Now